{"id":3674,"date":"2022-09-02T09:29:12","date_gmt":"2022-09-02T01:29:12","guid":{"rendered":"http:\/\/www.sinotau.com\/products\/florbetaben18finjection%ef%bc%88with-chinese-trade-name%e6%ac%a7%e9%9f%a6%e5%ae%81%ef%bc%89\/"},"modified":"2024-05-08T10:28:50","modified_gmt":"2024-05-08T02:28:50","slug":"neuraceq","status":"publish","type":"page","link":"http:\/\/www.sinotau.com\/en\/products\/neuraceq\/","title":{"rendered":"Florbetaben F 18 injection"},"content":{"rendered":"<div class=\"top\">\n<div class=\"container\">\n<div class=\"row\">\n<div class=\"col-md\">\n<div class=\"note\">\u6b64\u7f51\u7ad9\u4ec5\u4f9b\u4e2d\u56fd\u5c45\u6c11\u4f7f\u7528<\/div>\n<\/div>\n<div class=\"col-md-auto\">\n<ul class=\"nav\">\n<li>\u00a0<\/li>\n<li><a href=\"http:\/\/www.sinotau.com\/wp-content\/uploads\/2023\/12\/Highlightes-of-Prescribing-Information.pdf\">Download Prescribing Information<\/a><\/li>\n<\/ul>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"other-header\">\n<div class=\"container menu2 mb-media-6\">\n<div class=\"row align-items-center\">\n<div class=\"col-lg\">\n<div class=\"logo wow fadeInUp\"><img decoding=\"async\" src=\"\/wp-content\/uploads\/2023\/11\/\u6b27\u97e6\u5b81\u5546\u6807\u767d\u8272.png\" alt=\"logo\" \/><\/div>\n<\/div>\n<div class=\"col-lg-auto\">\n<ul class=\"nav wow fadeInUp\">\n<li class=\"active\"><a href=\"#about\">What is AD<\/a><\/li>\n<li><a href=\"#intro\">What is Florbetaben F 18 Injection<\/a><\/li>\n<li><a href=\"#petscan\">PET Scan<\/a><\/li>\n<li><a href=\"#support\">Patient Support<\/a><\/li>\n<\/ul>\n<\/div>\n<\/div>\n<\/div>\n<div id=\"about\" class=\"container\">\n<div class=\"txt\">\n<div class=\"sub wow fadeInUp\">What is AD<\/div>\n<h2 class=\"text48 title wow fadeInUp\">About AD<\/h2>\n<div class=\"des\">\n<p class=\"wow fadeInUp\"><span style=\"color: #ffffff;\">Alzheimer&#8217;s Disease (AD), an insidious neurodegenerative ailment, unfolds with a clandestine onset and progressive deterioration, comprising preclinical, mild cognitive impairment (MCI), and dementia stages. During the preclinical phase, patients typically manifest no overt cognitive decline or merely exhibit subjective cognitive descent. In the MCI stage, patients begin to experience cognitive impairments, particularly in memory. In the dementia stage, individuals gradually forfeit fundamental life capabilities, profoundly impacting the mental and physical well-being of the middle-aged and elderly, imposing a substantial burden on families and society.<\/span><\/p>\n<p class=\"wow fadeInUp\"><span style=\"color: #ffffff;\">With the ongoing escalation of population aging in China, the populace of AD patients is rapidly proliferating. A 2022 report from the international medical journal &#8220;The Lancet Public Health&#8221; reveals that there are presently approximately 10 million AD patients in China, with an anticipated surge to 30 million by 2030. Due to the limited awareness of the disease among patients and their families, coupled with the constrained diagnostic methods offered by hospitals, numerous patients are unable to receive timely diagnosis and treatment.<\/span><\/p>\n<p class=\"wow fadeInUp\"><span style=\"color: #ffffff;\">Urgent measures are to needed enhance the diagnosis and treatment of AD in response to the escalating burden of the disease in China, compounded by low rates of diagnosis and treatment. <\/span><\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<section class=\"page page-other-s1 container\">\n<div class=\"title-section\">\n<div class=\"sub\">What is AD<\/div>\n<h2 class=\"text48\">Six Stages of the AD Progression<\/h2>\n<\/div>\n<p>The abnormal deposition of \u03b2-amyloid neuritic plaques in the brain is the earliest pathological change in Alzheimer&#8217;s Disease (AD) and serves as a core biomarker for AD. Clinical practice often involves PET-CT\/PET-MRI scans to detect the level of A\u03b2 deposition in the brain, enabling the diagnosis, differential diagnosis, and efficacy assessment of AD.<\/p>\n<p>The progression of AD comprises six stages. In the first two stages, there are no apparent cognitive decline symptoms, making it challenging to identify. It is noteworthy that, during this period, \u03b2-amyloid neuritic plaques deposition is already present in the brain. As the disease advances and noticeable symptoms emerge in stages 3, 4, 5, and 6, A\u03b2 deposition in the brain may have been occurring for up to 20 years.<\/p>\n<div class=\"des\">\u00a0<\/div>\n<div class=\"box\">\n<div class=\"row g-xl-5 align-items-center\">\n<div class=\"col-lg\">\n<h3 class=\"text20\">Alzheimer&#8217;s disease (AD)course &#8211; six stages (2018 NIA-AA)<\/h3>\n<figure class=\"pic\"><img decoding=\"async\" src=\"\/wp-content\/uploads\/2023\/12\/Group-142-1.png\" alt=\"\" \/><\/figure>\n<\/div>\n<div class=\"col-lg-auto\">\n<div class=\"intro\">\n<p>AD has the characteristics of insidious onset and irreversible disease progression. Early diagnosis and intervention of the disease are the key to controlling disease progression.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/section>\n<section class=\"page page-other-s1 container\">\n<div class=\"title-section\">\u00a0<\/div>\n<\/section>\n<section id=\"intro\" class=\"page page-other-s2\">\n<div class=\"container\">\n<div class=\"row g-xl-5 align-items-center\">\n<div class=\"col-lg\">\n<div class=\"lc\">\n<div class=\"item\">\n<h3 class=\"text20\">Accurate diagnostic tool<\/h3>\n<p>It was demostrated that florbetaben F 18 injection is an accurate diagnostic tool for the estimation of beta-amyloid neuritic plaque in the living brain.<\/p>\n<\/div>\n<div class=\"item\">\n<h3 class=\"text20\">Only Active for a Short time<\/h3>\n<p>Florbetaben F 18 injection is radioactive but only stays active in the brain for a short time. More than half of it will be eliminated from the body within 2 hours of being injected.<\/p>\n<\/div>\n<div class=\"item\">\n<h3 class=\"text20\">No serious side effects<\/h3>\n<p>No serious side effects related to florbetaben F 18 injection use have been reported. All side effects wre mild to moderate and of short duration.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"col-lg\">\n<div class=\"rc\">\n<div class=\"sub\">What is Florbetaben F 18 Injection<\/div>\n<h2 class=\"text28\">Florbetaben F 18 injection\uff08with English trademark Neuraceqr<sup>\u00ae<\/sup>, and Chinese trademark \u6b27\u97e6\u5b81<sup>\u00ae<\/sup>) is the first domestically approved A\u03b2-PET imaging agent used for Alzheimer&#8217;s disease diagnosis.<\/h2>\n<div class=\"des\">\n<p>Florbetaben F 18 is an 18F-labeled diphenylethene derivative capable of specific binding to \u03b2-amyloid neuritic plaques in the cerebral cortex. The positron signals generated by the 18F isotope can be visualized through positron emission tomography (PET) scans, providing a direct depiction of the presence and spatial distribution of \u03b2-amyloid neuritic plaques in the brain.<\/p>\n<p>Florbetaben F 18 injection is the first domestically approved A\u03b2-PET imaging agent for Alzheimer&#8217;s disease (AD) diagnosis. It enables early, precise, and non-invasive diagnosis of AD, addressing a gap in the domestic market.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/section>\n<section id=\"petscan\" class=\"page page-other-s3\">\n<div class=\"container\">\n<div class=\"row g-xl-5 align-items-center\">\n<div class=\"col-lg-6\">\n<div class=\"txt\">\n<div class=\"sub\">PET SCAN<\/div>\n<h2 class=\"text48\">Advantages of PET scanning<\/h2>\n<div class=\"des\">PET scans are typically combined with CT scans to enhance diagnostic accuracy. Compared to traditional imaging, PET\/CT scans using Florbetaben F 18 injection can provide clear images of \u03b2-amyloid plaques, aiding both the subject and the clinician in making more precise treatment decisions.<\/div>\n<\/div>\n<\/div>\n<div class=\"col-lg-6\">\n<div class=\"wrap\">\n<div class=\"swiper petscanSliders\">\n<div class=\"swiper-wrapper\">\n<div class=\"swiper-slide\">\n<div class=\"item\">\n<div class=\"sub2\">Before PET\u00a0SCAN<\/div>\n<h3 class=\"text32\">Checklist<\/h3>\n<div class=\"des\">\n<p>The examinee should opt for comfortable clothing, avoiding garments with metal accessories, jewelry, glasses, etc., which must be removed before the examination.<\/p>\n<p>It is essential for the examinee to bring a list of all currently taken medications and share their medical history with the doctor.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"swiper-slide\">\n<div class=\"item\">\n<div class=\"sub2\">During PET\u00a0SCAN<\/div>\n<h3 class=\"text32\">workflows<\/h3>\n<div class=\"des\">\n<p>A florbetaben F 18 injection\u00a0PET\u00a0scan involves an injection into a vein in your arm and a short scan. After the injection, some saline solution (salt water) may be injected to help the florbetaben F 18 injection\u00a0move more quickly through the bloodstream.<\/p>\n<ul>\n<li>Injection\u2014\u2014the florbetaben F 18 injection injection is given through an iv(intravenous) tube.<\/li>\n<li>45+Minutes\u2014\u2014the florbetaben F 18 injection PET scan can be done 45 to 130 minutes after injection and usually lasts 15 to 20 minutes.<\/li>\n<li>During the scan\u2014\u2014During the scan, you will lie down on a table while the PET-scanner camera passes overhead.<\/li>\n<li>After the scan\u2014\u2014After the scan, an nuclear mdicine imaging specialist will view the results write a report, and send it to your doctor.<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"swiper-slide\">\n<div class=\"item\">\n<div class=\"sub2\">After PET\u00a0SCAN<\/div>\n<h3 class=\"text32\">Outcome<\/h3>\n<div class=\"des\">\n<p>The examinee should bring the examination reports for the clinician to review and make a diagnosis. The doctor will assess the results of the patient&#8217;s PET scan and other examinations, combining them with clinical manifestations, to determine whether the cognitive impairment in the patient may be attributed to Alzheimer&#8217;s Disease.<\/p>\n<p>The negative or positive scan results can assist both patients and physicians in clarifying the underlying causes.<\/p>\n<div class=\"row align-items-center\">\n<div class=\"col-2\"><img decoding=\"async\" src=\"\/wp-content\/uploads\/2023\/10\/\u56fe\u72471.png\" alt=\"\" \/><\/div>\n<div class=\"col-10\">\n<h3 class=\"text24\" style=\"margin: 0;\">A positive scan<\/h3>\n<\/div>\n<\/div>\n<p>If the florbetaben F 18 injection PET scan is positive, it can help your doctor figure out if you have AD. \u03b2-amyloid neuritic plaques are sticky clumps of protein that form in the brains of people who have AD. However, \u03b2-amyloid plaques may also be present in other diseases and in people without cognitive symptoms. These plaques affect the way the brain works. The presence of \u03b2-amyloid plaques is a key component for the confirmation of AD.<\/p>\n<div class=\"row align-items-center\">\n<div class=\"col-2\"><img decoding=\"async\" src=\"\/wp-content\/uploads\/2023\/10\/\u56fe\u72472.png\" alt=\"\" \/><\/div>\n<div class=\"col-10\">\n<h3 class=\"text24\" style=\"margin: 0;\">A Negative scan<\/h3>\n<\/div>\n<\/div>\n<p>If the florbetaben F 18 injection PET scan is negative, your doctor may consider different causes of cognitive impairment that are not due to AD.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"swiper-pagination\">\u00a0<\/div>\n<\/div>\n<div class=\"swiper-next\">\n<div class=\"iconfont icon-next\">\u00a0<\/div>\n<\/div>\n<div class=\"swiper-prev\">\n<div class=\"iconfont icon-prev\">\u00a0<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/section>\n<section id=\"support\" class=\"page page-other-s4 container\">\n<div class=\"sub\">Patient Support<\/div>\n<h2 class=\"text48\">How to communicate with your doctor<\/h2>\n<div class=\"des\">Notes on appointment and scanning of florbetaben F 18 injection<\/div>\n<div class=\"row\">\n<div class=\"col-lg-7\">\n<div class=\"row\">\n<div class=\"col\">\n<div class=\"item\" style=\"height: 100%;\">\n<div class=\"txt\" style=\"text-align: left;\">It&#8217;s advisable to have a relative or friend accompany you for the appointment and examination.<\/div>\n<\/div>\n<\/div>\n<div class=\"col\">\n<div class=\"item\" style=\"height: 100%;\">\n<div class=\"txt\" style=\"text-align: left;\">Please provide a list of all medications you are currently taking, along with essential medical history.<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"col-lg-5\">\n<div class=\"item3\" style=\"height: 100%;\">\n<div class=\"c1\">\n<h3 class=\"text20\">Come up with a list of questions you may have for the doctor.<\/h3>\n<ul>\n<li>Can you talk to me about PET \/ CT scans and their safety?<\/li>\n<li>Is a PET \/ CT scan with florbetaben F 18 injection the best choice for me?<\/li>\n<li>What did my florbetaben F 18 injection PET\u00a0scan show?<\/li>\n<li>What do my results mean?<\/li>\n<li>What else do you recommend?<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/section>\n<section class=\"page page-other-s5 container\">\n<div class=\"sub\">Patient Support<\/div>\n<h2 class=\"text48\">Frequently Asked Questions about Florbetaben F 18 injection<\/h2>\n<div class=\"question\">\n<div class=\"row\">\n<div class=\"col-md\">\n<div class=\"item open\">\n<div class=\"item-header\">\n<h3 class=\"title\">Who is florbetaben F 18 injection for?<\/h3>\n<\/div>\n<div class=\"item-body\">\n<div class=\"des\"><span style=\"color: revert; font-size: revert; font-weight: revert;\">Florbetaben F 18 injection is indicated for Positron Emission Tomography (PET) imaging of the brain to estimate \u03b2-amyloid neuritic plaque density in adult patients with cognitive impairment who are being evaluated for Alzheimer\u2019s Disease (AD) and other causes of cognitive decline.<\/span><\/div>\n<\/div>\n<\/div>\n<div class=\"item\">\n<div class=\"item-header\">\n<h3 class=\"title\">Does florbetaben F 18 injection diagnose Alzheimer&#8217;s disease?<\/h3>\n<\/div>\n<div class=\"item-body\">\n<div class=\"des\">\n<p>Your doctor will make a diagnosis based on the results of the Florbetaben F 18 injection PET scan, along with other examinations and observations. A negative florbetaben F 18 injection scan indicates sparse to no neuritic plaques and is inconsistent with a neuropathological diagnosis of AD at the time of image acquisition; a negative scan result reduces the likelihood that a patient\u2019 s cognitive impairment is due to AD. A positive florbetaben F 18 injection scan indicates moderate to frequent amyloid neuritic plaques; neuropathological examination has shown this amount of amyloid neuritic plaque is present in patients with AD, but may also be present in patients with other types of neurologic conditions as well as older people with normal cognition. Florbetaben F 18 injection is an adjunct to other diagnostic evaluations.<\/p>\n<p><u>Limitations of Use<\/u><\/p>\n<ul>\n<li>A positive florbetaben F 18 injection scan does not establish the diagnosis of AD or any other cognitive disorder.<\/li>\n<li>Safety and effectiveness of florbetaben F 18 injection have not been established for the follwing aspects.\n<ul>\n<li>Predicting development of dementia or other neurologic conditions<\/li>\n<li>Monitoring responses to therapies.<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"item\">\n<div class=\"item-header\">\n<h3 class=\"title\">What are some of the benefits of getting a florbetaben F 18 injection PET scan?<\/h3>\n<\/div>\n<div class=\"item-body\">\n<div class=\"des\">\n<p>Florbetaben F 18 injection\u00a0alone does not diagnose AD, it should be used in conjunction with other tests done by your doctor to make a diagnosis. Having a diagnosis allows you (and\/or your loved one) to be involved in planning the path forward. Being able to participate early in the planning of care and other important decisions, such as finances, allows you to have more control in making the decisions that are right for you.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"col-md\">\n<div class=\"item\">\n<div class=\"item-header\">\n<h3 class=\"title\">Does a florbetaben F 18 injection PET scan suits me\uff1f<\/h3>\n<\/div>\n<div class=\"item-body\">\n<div class=\"des\">Only your doctor can determine if a florbetaben F 18 injection\u00a0PET\u00a0scan is appropriate for you.<\/div>\n<\/div>\n<\/div>\n<div class=\"item\">\n<div class=\"item-header\">\n<h3 class=\"title\">What are the important safety information of florbetaben F 18 injection?<\/h3>\n<\/div>\n<div class=\"item-body\">\n<ul>\n<li>Risk for Image Misinterpretation and Other Errors<br \/>Errors may occur in the florbetaben F 18 injection estimation of brain neuritic \u03b2-amyloid plaque density during image interpretation. Image interpretation should be performed independently of the patient\u2019s clinical information. The use of clinical information in the interpretation of florbetaben F 18 injection images has not been evaluated and may lead to errors. Errors may also occur in cases with severe brain atrophy that limits the ability to distinguish gray and white matter on the florbetaben F 18 injection scan. Errors may also occur due to motion artifacts that result in image distortion. Florbetaben F 18 injection scan results are indicative of the presence of brain neuritic \u03b2-amyloid plaques only at the time of image acquisition and a negative scan result does not preclude the development of brain neuritic \u03b2-amyloid plaques in the future.<\/li>\n<li>Radiation Risk<br \/>Florbetaben F 18 injection, similar to other radiopharmaceuticals, contributes to a patient&#8217;s overall long-term cumulative radiation exposure. Long-term cumulative radiation exposure is associated with an increased risk of cancer. Ensure safe handling to protect patients and health care workers from unintentional radiation exposure.<\/li>\n<li>Overdosage<br \/>A pharmacological overdose of florbetaben F 18 injection is unlikely given the relatively low doses used for diagnostic purposes. In the event of administration of a radiation overdose with florbetaben F 18 injection, the absorbed organ dose to the patient should be reduced by increasing elimination of the radionuclide from the body by inducing frequent micturition.<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<div class=\"item\">\n<div class=\"item-body\">\n<div class=\"des\">\u00a0<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/section>\n<section class=\"page page-other-s6\">\n<div class=\"container\">\n<h2 class=\"text32 text-center mb-media-3\">Important Information of Florbetaben F 18 Injection<\/h2>\n<div class=\"row g-3\">\n<div class=\"col-md-12 col-lg-4\">\n<div class=\"item\">\n<div class=\"icon\"><img decoding=\"async\" src=\"\/wp-content\/uploads\/2023\/11\/zaoqi.svg\" alt=\"\" \/><\/div>\n<h3>Early diagnosis<\/h3>\n<div class=\"des\">Guidelines and consensus consistently recommend the use of beta-amyloid PET detection for early diagnosis and differential diagnosis of Alzheimer&#8217;s Disease (AD).<\/div>\n<div>\u00a0<\/div>\n<ul>\n<li class=\"des\">Beta-amyloid PET serves as a core biomarker in the imaging examination of AD.<\/li>\n<li class=\"des\">Positive imaging results have been observed as early as 15-20 years before the onset of dementia symptoms.<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<div class=\"col-md-6 col-lg-4\">\n<div class=\"item\">\n<div class=\"icon\"><img decoding=\"async\" src=\"\/wp-content\/uploads\/2023\/11\/jingzhun.svg\" alt=\"\" \/><\/div>\n<h3>Accurate<\/h3>\n<div class=\"des\">Florbetaben F 18 injection, through detection, precisely identifies beta-amyloid plaques in AD patients.<\/div>\n<ul>\n<li style=\"text-align: left;\">High sensitivity and specificity.<\/li>\n<li style=\"text-align: left;\">Reveals the pathological spatial distribution.<\/li>\n<li style=\"text-align: left;\">Facilitates visual qualitative interpretation.<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<div class=\"col-md-6 col-lg-4\">\n<div class=\"item\">\n<div class=\"icon\"><img decoding=\"async\" src=\"\/wp-content\/uploads\/2023\/11\/wuchaugn.svg\" alt=\"\" \/><\/div>\n<h3>Non-invasive<\/h3>\n<div class=\"des\">The detection method of Florbetaben F 18 injection is non-invasive and highly practical, avoiding discomfort and potential complications associated with invasive procedures.<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/section>\n\n\n\n","protected":false},"excerpt":{"rendered":"<p>\u6b64\u7f51\u7ad9\u4ec5\u4f9b\u4e2d\u56fd\u5c45\u6c11\u4f7f\u7528 \u00a0 Download Prescribing Information What is AD What is Florbetaben F 18 Injection PET Scan Patient Support What is AD About AD Alzheimer&#8217;s Disease (AD), an insidious neurodegenerative ailment, unfolds with a clandestine onset and progressive deterioration, comprising preclinical, mild cognitive impairment (MCI), and dementia stages. During the preclinical phase, patients typically manifest no [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":3628,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"products.php","meta":{"inline_featured_image":false,"footnotes":""},"class_list":["post-3674","page","type-page","status-publish","hentry"],"meta_box":{"salary":[],"career":[]},"_links":{"self":[{"href":"http:\/\/www.sinotau.com\/en\/wp-json\/wp\/v2\/pages\/3674","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/www.sinotau.com\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"http:\/\/www.sinotau.com\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"http:\/\/www.sinotau.com\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.sinotau.com\/en\/wp-json\/wp\/v2\/comments?post=3674"}],"version-history":[{"count":47,"href":"http:\/\/www.sinotau.com\/en\/wp-json\/wp\/v2\/pages\/3674\/revisions"}],"predecessor-version":[{"id":4523,"href":"http:\/\/www.sinotau.com\/en\/wp-json\/wp\/v2\/pages\/3674\/revisions\/4523"}],"up":[{"embeddable":true,"href":"http:\/\/www.sinotau.com\/en\/wp-json\/wp\/v2\/pages\/3628"}],"wp:attachment":[{"href":"http:\/\/www.sinotau.com\/en\/wp-json\/wp\/v2\/media?parent=3674"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}